However, at 14 days of age, the offspring of HF-fed dams showed a higher body weight and an increased fat deposition. The HF group had significantly heavier pancreata than the LF group, but this did not correspond with the protein concentration, which was significantly lower Table 4.
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Studies on human lactation. The stomach contents were saved on ice. In the HF group of pups, no major differences in thymus and spleen weight were observed, as compared with lean controls, whereas the HF-EC group showed large increases in these immune organs.
The stomach was removed, rinsed in saline and weighed. Biochem J. One day after birth, no significant differences in body weight were observed between the groups. In the additional study, the spleen weighed more in the HF group as compared with the LF group thymus weight was not investigated Table 1b.
This stresses the need for more extensive studies on the significance of the maternal diet and colonizing microflora in neonates. Since fat pad weights differ between males and females, only males were used in the study.
The blood plasma levels of the acute-phase protein, haptoglobin, were significantly elevated in the HF group as compared with the LF group Figure 3and the HF-EC group showed even higher levels as compared with the HF group.
Analyses Disaccharidase activities in the SI Intestinal disaccharidase activities was measured using the Dahlqvist method. Consequently, the resulting experimental groups have been as followed: Forty lactating multiparous Yorkshire sows were used to test the hypothesis that reducing dietary CP and supplementing with crystalline amino acids CAA increases dietary N utilization for milk production during early and peak lactation.
Table 1a: The rats had free access to tap water.
March 9, Copyright: Attempted abortion with aminopterin 4-amino-pteroylglutamic acid ; malformations of the child. The transmission of vitamin A from parents to young in mammals. In peak lactation, N retention We determined glucose-tolerance and measured cardiovascular parameters using a tip-catheter.
In short, plasma was incubated with hemoglobin, which bound to haptoglobin present in the samples leading to preservation of peroxidase activity of the hemoglobin. The present study demonstrates for the first time how bacterial administration to the maternal diet during the neonatal period can affect body weight and fat deposition in the offspring.
During this period, the brush border disaccharidases of the SI shift from a high lactase activity and low maltase and sucrase activity to a reversed adult-type pattern. In the present study, we investigated the effects of maternal HF feeding and oral administration of bacteria on the physiology of the offspring.
August 27, ; Accepted: Marker molecule levels in blood plasma The intestinal permeability was determined by measuring the concentrations of the marker molecules BSA and BIgG in blood samples taken 3 h after gavage.
It is possible that the presumable higher fat content of the mother's milk led to an energy-demanding adaptation of the pancreas to produce lipase, at the cost of stomach and SI functional development.
Furthermore, the weights of both the epididymal and the retroperitoneal fat pads were significantly increased in the HF group as compared with the LF group, and the HF-EC group had significantly heavier fat pads than the HF group Figure 2b.
All offspring were monitored up to days after birth. Conclusions The present study using a rat model shows that a maternal diet high in fat has a profound impact on body growth, fat deposition and GI function in the suckling offspring.
However, the use of the out-bred Sprague—Dawley rat strain maximizes genetic differences between the litter mates, as well as the use of different males for mating in each group.
Pancreas weight and protein content mg ml—1 per g tissue of day-old rat pups born from dams fed either a high fat diet with or without addition of E.
Only male pups were used in the study so that epididymal fat pad weights could be compared. Still, it is possible that the bacterial supplement to the mothers altered the resident Enterobacteriaceae community in the offspring, which affected body weight and fat deposition in the offspring.
The particular strain used here, E. PNAS ; After opening the bowel and chest, the pups were exsanguinated by taking 0.
The assay sensitivity was reported to be 0.
Bacterial colonies on violet red bile glucose agar plates were considered to be bacteria belonging to the family Enterobacteriaceae. The SI, however, showed increased length in HF offspring, which may promote nutrient absorption.
Sows were assigned to 1 of 4 diets: Small intestinal proximal part protein concentration mg ml—1 and disaccharidase activities U ml—1 of day-old rat pups born from dams fed either a high-fat diet with or without addition of E. · Feeding lactating diets reduced in CP from % to % with CAA inclusion as partial replacement for limiting AA improved N retention and N utilization efficiency for milk protein production in peak lactation, while these effects were less pronounced in early laurallongley.com by: 9.
The effect of metabolizable energy intake (,and MJ day −1) and protein sources on the milk yield of Finn Dorset ewes in early lactation: basal diet of hay and barley. to examine the impact of maternal isocaloric high-protein diet during pregnancy and lactation on metabolic and cardiovascu- lar phenotype of the offspring in rats.
There were two temporally different patterns of milk protein gene expression during the lactation cycle: One group of genes is induced to high levels around parturition and is expressed throughout lactation, and a second group of genes is expressed highly only during specific phases of lactation (Sharp et al., ; Simpson and Nicholas, ).
diet containing a high (HP, % lysine) or low(LP,% lysine) protein content during a d lactation. Dietary lysine concentration was achieved by altering.
The most striking finding in the offspring group with high-protein diet during lactation was a significant association with sucklings' survival (P = ).